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Algumas pessoas ficam com o rosto avermelhado logo após consumir bebidas alcoólicas, e isso pode estar relacionado ao acúmulo de acetaldeído, uma substância produzida durante o metabolismo do álcool. Normalmente, o etanol é transformado em acetaldeído e, em seguida, outra enzima, a aldeído desidrogenase , converte esse composto em acetato, que é muito menos tóxico. Em algumas pessoas, porém, essa segunda etapa é menos eficiente por causa de variantes genéticas da ALDH2, favorecendo o acúm
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