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Ambas pertencem à mesma classe de antidepressivos: os ISRS, inibidores seletivos da recaptação de serotonina. A associação entre elas não aumenta a eficácia, mas multiplica os riscos. Quando combinadas, a chance de efeitos colaterais cresce, como náusea, insônia, disfunção sexual e agitação. O risco mais grave é o desenvolvimento da síndrome serotoninérgica, uma condição potencialmente perigosa, marcada por febre, confusão mental, hipertensão, tremores e alterações neuromusculares. Por isso, n
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O fator de risco nesta classe é um pouco alto.
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